East San Diego Homes with Mixed Use Subtype

Welcome to East San Diego, a vibrant and diverse community nestled in the heart of California's sunny San Diego County. Known for its eclectic blend of urban living and suburban charm, East San Diego offers a unique lifestyle that caters to both families and young professionals alike. With its picturesque neighborhoods, stunning parks, and close proximity to downtown San Diego, this area is perfect for those seeking a lively yet relaxed atmosphere.

One of the standout features of East San Diego is its mixed-use properties, which beautifully blend residential and commercial spaces. These homes with a mixed-use subtype provide a perfect opportunity for homeowners and entrepreneurs to live and work in the same vibrant environment. Imagine waking up in your stylish loft, stepping out to grab a coffee from your favorite local café, and then heading down to your own boutique or office, all within a short stroll from your front door.

The mixed-use developments in East San Diego not only encourage a sense of community but also foster a dynamic lifestyle where convenience and creativity thrive. Residents can enjoy an array of amenities, including shops, restaurants, and recreational spaces, all designed to enhance the quality of life.

Whether you’re looking for a cozy apartment or a spacious townhouse, East San Diego’s mixed-use homes offer countless possibilities for living and working in harmony. Embrace the opportunity to be part of this thriving community where the best of urban and suburban life come together, making East San Diego a truly exceptional place to call home.

Newest East San Diego Homes with Mixed Use Subtype

$1,600,000

260017277SD MLS ⋅ Active Status

Attention Investors and Developers! This is an incredible opportunity to own an income property with the potential to add six additional units with approved zoning (see documents), expanding the current six-unit property to a possible twelve units. Situated on just under half an acre at the end of a quiet cul-de-sac, this property offers both privacy and convenient access to major commuter routes. With six existing units—three 2-bedroom, 1-bath units and two 1-bedroom, 1-bath units and a studio—the investment potential is outstanding. The property features two separate buildings, with four units in the main building and two units in the second building, plus plenty of parking for tenants, both in the front and back. Built in 1958, this property presents a rare chance for investors or developers to significantly increase rental income and maximize the value of the lot. Opportunities like this are hard to find—don’t miss out.

2499 Tuberose St, East San Diego

$2,400,000

260015351SD MLS ⋅ Active Status

Pleased to present this Garden Style 10 Unit Apartment Building located on the western side of City Heights, just a few blocks from the I-15 Interstate. The property offers a Walk Score of 88/100 and is conveniently situated near several grocery stores and restaurants. 3770 42nd Street provides access to multiple elementary, middle, and high schools within a short walk or drive. City Heights continues to improve year over year in terms of overall property conditions and tenant quality. This is the perfect “bread & butter” property that attracts quality tenants and should provide a stable, cash-flowing investment for the next owner. Significant capital improvements have been completed, including main and subpanel electrical replacements for insurance compliance, a roof approximately seven years old, and the recent replacement of more than half of the water heaters. SB 721 work has been completed, with a passing inspection report available upon completion of the final inspection scheduled for next week. The Property has been well maintained over the years by a well respected Property Management Company. The mix consists of 7 1BR/1Bath & Three 2BR/1Bath units. Nearby units are achieving rents approximately 10% higher.

3770 42nd Street, East San Diego

$3,500,000

260014678SD MLS ⋅ Active Status

4022 42nd Street is an upgraded turnkey 11-unit apartment community located in a central San Diego neighborhood, offering immediate cash flow, long-term upside, and a stabilized, low-maintenance investment opportunity. The property features a diverse unit mix of five 2BR/1BA units, four 1BR/1BA units, and two brand-new ADUs with modern finishes and efficient layouts. The secure gated complex has been thoughtfully renovated and professionally maintained, with amenities including off-street parking, on-site laundry, and a private setting for residents. With strong rental demand, quality improvements, and an attractive unit mix, 4022 42nd Street presents a compelling opportunity for multifamily investors seeking a turnkey income-producing asset in San Diego.

4022 42Nd, East San Diego

$1,295,000

260011373SD MLS ⋅ Active Status

We are proud to present an exceptional investment opportunity in the heart of City Heights, San Diego. This impressive property features a 3,351 square foot building comprising a two-bedroom, one bath house in the front, and four 1-bedroom, 1 bath apartments in the back. These 5 well-maintained units are perfect for a prospective multifamily investor. Renovated in 2009, the property offers modern amenities and a well-maintained interior to attract discerning tenants. New gas lines and a reinforced foundation were recently installed in the front home. The property has an on-site laundry room and ample parking. This investment promises a stable income stream and future growth potential. Take advantage of this prime opportunity to own a sought-after property in the thriving City Heights neighborhood, where demand for quality housing remains consistently high.

4135 Chamoune Avenue, East San Diego

$8,995,000

260007745SD MLS ⋅ Active Status

Rare investment opportunity featuring a $48,000/month NNN master lease with House of Metamorphosis, a well-established nonprofit operator with approximately 50 years in business, delivering stable, predictable income with minimal landlord responsibility. The property consists of 26 units, each with a private bathroom, purposefully designed for supervised residential care. The 8,450 SF building offers an average unit size of approximately 325 SF, maximizing income efficiency. Situated on a 7,000 SF lot with motel zoning, the property presents limited land value contribution; however, the zoning carries significant embedded entitlement value for SRO and behavioral health uses—an increasingly scarce and difficult-to-replicate asset class in San Diego. Investors are presented with a dual-path opportunity: continue operating with a reputable, long-term tenant under a true NNN structure, or reposition the asset for alternative residential or lodging uses, leveraging the existing 26-unit configuration and flexible zoning.

4017 42nd St, East San Diego

$2,170,000

260006407SD MLS ⋅ Active Status

Excellent opportunity to own an 8-unit property well located in San Diego. Four units feature 2 bedrooms and 1 bathroom, while the remaining four units offer 1 bedroom and 1 bathroom. Each unit includes a designated parking space, and the property features an on-site laundry room.The property is conveniently situated near schools, shopping, dining, and major freeways, offering strong rental appeal.Property is currently tenant-occupied. Do not disturb occupants. Buyer to verify all information.A great opportunity to secure a high-demand investment property don't miss this chance.

3805 Winona Ave, East San Diego

$2,275,000

250042932SD MLS ⋅ Active Status

4062 49th Street is a 9-unit complex in City Heights with plenty of parking. The 5,190 square foot building built in 1968 is situated on a 5,739 square foot lot. There are nine 1 Bedroom / 1 Bathroom units. All units have been completely remodeled in 2025. There was a new roof installed as well as stucco repair, exterior repaint, new security doors, and water proofing of the balconies. All unit interiors feature new canned lighting, window coverings and vinyl plank flooring with new baseboards. All units have new appliances and electric wall heaters powered by new sub panels. Plumbing was replaced with copper and ABS as needed. The kitchens and bathrooms feature new cabinets, fixtures, hardware, and quartz countertops. There is an onsite laundry facility that has been expanded and has new machines. The property is located in City Heights, close to the transit and shopping off El Cajon Blvd.

4062 49th Street, East San Diego

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Based on information from California Regional Multiple Listing Service, Inc. as of . This information is for your personal, non-commercial use and may not be used for any purpose other than to identify prospective properties you may be interested in purchasing. Display of MLS data is usually deemed reliable but is NOT guaranteed accurate by the MLS. Buyers are responsible for verifying the accuracy of all information and should investigate the data themselves or retain appropriate professionals. Information from sources other than the Listing Agent may have been included in the MLS data. Unless otherwise specified in writing, Broker/Agent has not and will not verify any information obtained from other sources. The Broker/Agent providing the information contained herein may or may not have been the Listing and/or Selling Agent.